SynapCalm AG+ Serum 30mL

Advanced Expression-Line Smoothing Serum

A concentrated peptide serum designed to visibly soften expression lines while promoting smoother, firmer and more hydrated-looking skin.

SynapCalm AG+ combines Acetyl Hexapeptide-8, sodium hyaluronate, panthenol and antioxidant-rich Laminaria digitata extract in a lightweight daily formula. It targets the visible appearance of expression-prone areas, including the forehead, crow’s feet and lines between the eyebrows.

Known within the Pravélune™ collection as our “Botox in a Bottle” serum, SynapCalm AG+ offers a topical, needle-free approach to maintaining a smooth and refreshed-looking complexion. This descriptive beauty phrase does not mean that the serum contains botulinum toxin or produces the same effects as injectable treatments.

Why You’ll Love It

SynapCalm AG+ provides targeted peptide care for visible expression lines without introducing a heavy or greasy texture. Its hydrating formula layers comfortably into both morning and evening routines while helping the skin appear smoother, plumper and more refined.

Key Benefits

• Visibly softens the appearance of expression lines
• Helps smooth the look of forehead lines and crow’s feet
• Hydrates and visibly plumps dehydration lines
• Supports firmer and more resilient-looking skin
• Helps protect against visible environmental stress
• Promotes a refreshed and youthful-looking complexion

Ingredient Science

Acetyl Hexapeptide-8

A signal peptide commonly associated with the trade ingredient Argireline®. It is used in advanced cosmetic formulations to help visibly soften the appearance of expression-related lines and promote smoother-looking skin.

Laminaria Digitata Extract

A mineral-rich brown seaweed extract with antioxidant and skin-conditioning properties. It helps support more resilient, revitalized-looking skin while protecting against visible environmental stress.

Sodium Hyaluronate

A moisture-binding form of hyaluronic acid that attracts hydration and helps visibly plump fine dehydration lines.

Panthenol

Also known as pro-vitamin B5, panthenol helps hydrate, soothe and support the skin’s moisture barrier.

Glycerin

A proven humectant that draws moisture toward the skin to support lasting softness and hydration.

Who It’s For

SynapCalm AG+ is recommended for those concerned with:

• Forehead expression lines
• Crow’s feet
• Lines between the eyebrows
• Early visible signs of ageing
• Fine dehydration lines
• Loss of firmness
• Dry or moisture-depleted skin
• Maintaining smoother-looking skin between professional treatments

Suitable for normal, dry, combination, oily and mature-looking skin.

Texture and Finish

A lightweight, fast-absorbing serum that leaves the skin feeling smooth and hydrated without a heavy or greasy finish.

How to Use

1. Cleanse the skin with L’Essence de Grace Gentle Cleanser.
2. Apply your preferred Pravélune™ toner.
3. Dispense a small amount of SynapCalm AG+ onto clean fingertips.
4. Apply across the face or concentrate on the forehead, between the eyebrows and around the outer eye area.
5. Gently press the serum into the skin until absorbed.
6. Follow with moisturizer.
7. Complete your morning routine with broad-spectrum sunscreen.

Use consistently in the morning and evening.

Avoid direct contact with the eyes, eyelids and broken or irritated skin. Patch testing is recommended before first use.

Complete Your Routine

Morning

1. L'Essence de Grâce "Gentle Cleanser" 100mL – Pravélune
2. R.B.R. Mineral Toner "Skin Softening & PH Balancing Toner" 50mL – Pravélune
3. SynapCalm AG+ Smoothing Peptide Serum 30mL | Pravélune – Pravélune
4. Roséa Eye Crème "Under Eye Cream for Dark Circles & Fine Lines" 15mL – Pravélune
5. VeriCalm B5 Cica "Tailored Specifically for Skin Recovery" 50mL – Pravélune or Aura Nexa Riche "The Ultimate Moisturizing Cream" 50mL – Pravélune
6. Broad-spectrum sunscreen

Evening

1. L'Essence de Grâce "Gentle Cleanser" 100mL – Pravélune
   
2. R.B.R. Mineral Toner "Skin Softening & PH Balancing Toner" 50mL – Pravélune
3. SynapCalm AG+ Smoothing Peptide Serum 30mL | Pravélune – Pravélune
4. Segentis Peptide™ "Advanced Peptide & Amino Acid Face Serum" 30mL – Pravélune
5. Roséa Eye Crème "Under Eye Cream for Dark Circles & Fine Lines" 15mL – Pravélune
6. VeriCalm B5 Cica "Tailored Specifically for Skin Recovery" 50mL – Pravélune or Aura Nexa Riche "The Ultimate Moisturizing Cream" 50mL – Pravélune

Complete Ingredient List

Aqua, Acetyl Hexapeptide-8, Glycerin, Sodium Hyaluronate, Laminaria Digitata Extract, Panthenol, Diazolidinyl Urea, Iodopropynyl Butylcarbamate and Propylene Glycol.

The final published INCI should match the ingredient list printed on the finished packaging exactly.

The Pravélune™ Promise

At Pravélune™, regenerative skincare is intentionally crafted to support elevated skin health. Our formulas combine purposeful ingredients with a refined, science-led approach to help your skin look balanced, resilient and luminous. Every product is designed to transform your daily routine into an elevated ritual of care.

Made in Canada • Laboratory Formulated • Science-Backed • Cruelty-Free